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Mouse Anti-ZNF224 Recombinant Antibody (2C12) (CBMAB-Z0424-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2C12
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
ZNF224 (AA95-190) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.5 mg/mL

Target

Full Name
zinc finger protein 224
Introduction
ZNF224 (Zinc Finger Protein 224) is a Protein Coding gene. Diseases associated with ZNF224 include Wilms Tumor 1. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF225.
Entrez Gene ID
7767
UniProt ID
Q9NZL3
Alternative Names
BMZF2; KOX22; ZNF27; BMZF-2; ZNF233; ZNF255
Function
May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Biological Process
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:NTNU_SB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
Colocalizes with DEPDC1A at the nucleus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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