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Mouse Anti-ZHX1 Recombinant Antibody (5E5) (CBMAB-Z0252-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
5E5
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
ZHX1 (AA731-829) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid

Target

Full Name
zinc fingers and homeoboxes 1
Introduction
ZHX1 (Zinc Fingers And Homeoboxes 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription corepressor activity. An important paralog of this gene is ZHX2.
Entrez Gene ID
11244
UniProt ID
Q9UKY1
Alternative Names
Zinc Fingers And Homeoboxes 1
Function
Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.
Biological Process
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
Colocalized in the nucleus with DNMT3B.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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