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Mouse Anti-YBX3 (AA 241-330) Recombinant Antibody (CBFYC-3227) (CBMAB-C3305-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-3227
Antibody Isotype
IgG2a, k
Application
ELISA, IF, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 241-330

Target

Full Name
YBX3
Introduction
YBX3 (Y-Box Binding Protein 3) is a Protein Coding gene. Diseases associated with YBX3 include Lyme Disease and Uterine Inflammatory Disease. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Bisphosphonate Pathway, Pharmacodynamics. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is YBX1.
Entrez Gene ID
8531
UniProt ID
P16989
Alternative Names
Y-Box Binding Protein 3; Single-Strand DNA-Binding Protein NF-GMB; Cold Shock Domain-Containing Protein A; Cold-Shock Domain Containing A1; DNA-Binding Protein A; CSDA; DBPA
Function
Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).
Biological Process
Biological Process 3'-UTR-mediated mRNA stabilization Source:BHF-UCL1 Publication
Biological Process apoptotic process Source:Ensembl
Biological Process cellular hyperosmotic response Source:BHF-UCL1 Publication
Biological Process cellular response to tumor necrosis factor Source:BHF-UCL1 Publication
Biological Process ectopic germ cell programmed cell death Source:Ensembl
Biological Process fertilization Source:Ensembl
Biological Process in utero embryonic development Source:Ensembl
Biological Process male gonad development Source:Ensembl
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress Source:BHF-UCL1 Publication
Biological Process negative regulation of necroptotic process Source:BHF-UCL1 Publication
Biological Process negative regulation of reproductive process Source:Ensembl
Biological Process negative regulation of skeletal muscle tissue development Source:Ensembl
Biological Process negative regulation of transcription by RNA polymerase II Source:Ensembl
Biological Process positive regulation of cytoplasmic translation Source:BHF-UCLBy Similarity
Biological Process positive regulation of organ growth Source:Ensembl
Biological Process regulation of gene expression Source:GO_Central1 Publication
Biological Process spermatogenesis Source:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

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