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Rabbit Anti-VSTM5 Recombinant Antibody (CBYCV-128) (CBMAB-V0084-YC)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBYCV-128
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
V-Set And Transmembrane Domain Containing 5
Introduction
VSTM5 (V-Set And Transmembrane Domain Containing 5) is a protein coding gene. Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. VSTM5 is involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, VSTM5 regulates synapse formation by altering dendritic spine morphology and actin distribution and promotes formation of unstable neuronal spines such as thin and branched types. VSTM5 regulates neuronal morphogenesis and migration during cortical development in the brain.
Entrez Gene ID
Human387804
Mouse69137
Rat500947
UniProt ID
HumanA8MXK1
MouseQ9D806
RatQ5M7U7
Alternative Names
V-Set And Transmembrane Domain Containing 5; C11orf90; V-Set And Transmembrane Domain-Containing Protein 5; Chromosome 11 Open Reading Frame 90
Function
Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical development in the brain.
Biological Process
Biological Process filopodium assembly Source:UniProtKB
Biological Process positive regulation of excitatory synapse assembly Source:UniProtKB
Biological Process protein homooligomerization Source:UniProtKB
Biological Process ventral spinal cord development Source:Ensembl
Cellular Location
Cell membrane
Cell projection, dendrite
Cell projection, axon
Topology
Extracellular: 29-147
Helical: 148-168
Cytoplasmic: 169-200
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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