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Rabbit Anti-VSIG4 Recombinant Antibody (202) (CBMAB-V0072-YC)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
202
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Recombinant Human VSIG4 Protein (Catalog#12163-H08H)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
V-Set And Immunoglobulin Domain Containing 4
Introduction
VSIG4 is a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins.
Entrez Gene ID
11326
UniProt ID
Q9Y279
Alternative Names
V-Set And Immunoglobulin Domain Containing 4; Protein Z39Ig; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Ig Superfamily Protein
Function
Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
Biological Process
Biological Process complement activation, alternative pathway Source:UniProtKB-KW
Biological Process negative regulation of complement activation, alternative pathway Source:UniProtKB1 Publication
Biological Process negative regulation of interleukin-2 production Source:GO_Central1 Publication
Biological Process negative regulation of macrophage activation Source:InterPro
Biological Process negative regulation of T cell proliferation Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 20-283
Helical: 284-304
Cytoplasmic: 305-399
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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