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Mouse Anti-VIP Recombinant Antibody (CBYY-1517) (CBMAB-1586-YY)


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Summary

Host Animal
Mouse
Specificity
Human, Rat, Pig, Cattle
Clone
CBYY-1517
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Vasoactive intestinal peptide
Specificity
Human, Rat, Pig, Cattle
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vasoactive Intestinal Peptide
Introduction
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforMouse have been identified.
Entrez Gene ID
Human7432
Rat117064
Cattle280956
Pig100500718
UniProt ID
HumanP01282
RatP01283
CattleP81401
PigP01284
Alternative Names
Vasoactive Intestinal Peptide; Prepro-VIP; VIP Peptides; PHuman27;
Function
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathway Source:BHF-UCL1 Publication
Biological Process antibacterial humoral response Source:UniProtKB
Biological Process antifungal humoral response Source:UniProtKB
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptide Source:UniProtKB
Biological Process body fluid secretion Source:ProtInc1 Publication
Biological Process defense response to Gram-negative bacterium Source:UniProtKB
Biological Process defense response to Gram-positive bacterium Source:UniProtKB
Biological Process epinephrine secretion Source:GO_Central1 Publication
Biological Process G protein-coupled receptor signaling pathway Source:ProtInc1 Publication
Biological Process innate immune response Source:UniProtKB
Biological Process learning or memory Source:GO_Central1 Publication
Biological Process mRNA stabilization Source:AgBase
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process negative regulation of potassium ion transport Source:GO_Central1 Publication
Biological Process negative regulation of smooth muscle cell proliferation Source:GO_Central1 Publication
Biological Process phospholipase C-activating G protein-coupled receptor signaling pathway Source:GO_Central1 Publication
Biological Process positive regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of endothelial cell proliferation Source:GO_Central1 Publication
Biological Process positive regulation of epinephrine secretion Source:GO_Central1 Publication
Biological Process positive regulation of penile erection Source:GO_Central1 Publication
Biological Process positive regulation of protein catabolic process Source:BHF-UCL1 Publication
Biological Process prolactin secretion Source:AgBase
Biological Process regulation of protein localization Source:BHF-UCL1 Publication
Biological Process regulation of sensory perception of pain Source:GO_Central1 Publication
Biological Process response to yeast Source:UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

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