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Rabbit Anti-VEGFB Recombinant Antibody (BA0267) (CBMAB-0961CQ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
BA0267
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Synthetic peptide from a region within Human VEGFB
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vascular Endothelial Growth Factor B
Introduction
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Entrez Gene ID
7423
UniProt ID
P49765
Alternative Names
VRF; VEGFL
Function
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Biological Process
Biological Process cardiac muscle contraction Source:Ensembl
Biological Process coronary vasculature development Source:Ensembl
Biological Process induction of positive chemotaxis Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB
Biological Process negative regulation of gene expression Source:UniProtKB
Biological Process negative regulation of neuron apoptotic process Source:UniProtKB
Biological Process positive regulation of angiogenesis Source:GO_Central1 Publication
Biological Process positive regulation of cell division Source:UniProtKB-KW
Biological Process positive regulation of endothelial cell proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of ERK1 and ERK2 cascade Source:UniProtKB
Biological Process positive regulation of mast cell chemotaxis Source:UniProtKB1 Publication
Biological Process positive regulation of peptidyl-tyrosine phosphorylation Source:UniProtKB
Biological Process positive regulation of protein kinase B signaling Source:UniProtKB
Biological Process positive regulation of protein phosphorylation Source:GO_Central1 Publication
Biological Process positive regulation of vascular endothelial growth factor receptor signaling pathway Source:UniProtKB
Biological Process positive regulation of vascular wound healing Source:UniProtKB
Biological Process protein O-linked glycosylation Source:Ensembl
Biological Process response to hypoxia Source:GO_Central1 Publication
Biological Process sprouting angiogenesis Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor receptor signaling pathway Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor signaling pathway Source:GO_Central1 Publication
Cellular Location
Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
PTM
VEGF-B186 is O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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