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Mouse Anti-VAT1 Recombinant Antibody (CBYY-1286) (CBMAB-1304-YY)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBYY-1286
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
vesicle amine transport protein 1 homolog (T. californica)
Introduction
Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins.
Entrez Gene ID
Human7409
Mouse22324
Rat25156
UniProt ID
HumanP15498
MouseP27870
RatP54100
Alternative Names
Vesicle Amine Transport 1; Vesicle Amine Transport Protein 1 Homolog (T. Californica); Membrane Protein Of Cholinergic Synaptic Vesicles; Synaptic Vesicle Membrane Protein VAT-1 Homolog; EC 1.-.-.-; VATI;
Function
Possesses ATPase activity (By similarity).
Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).
Biological Process
Biological Process negative regulation of mitochondrial fusion Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Mitochondrion outer membrane
The majority is localized in the cytoplasm and a small amount is associated with mitochondria.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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