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Rabbit Anti-TSC22D1 Recombinant Antibody (CBYJT-4964) (CBMAB-T4521-YJ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBYJT-4964
Antibody Isotype
IgG
Application
ICC, IF

Basic Information

Immunogen
Recombinant Human TSC22D1 Protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TSC22D1
Introduction
TSC22D1 is a member of the TSC22 domain family of leucine zipper transcription factors. TSC22D1 is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. TSC22D1 may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy.
Entrez Gene ID
8848
UniProt ID
Q15714
Alternative Names
TSC22 Domain Family Member 1; Transforming Growth Factor Beta-1-Induced Transcript 4 Protein; TGFB-Stimulated Clone 22 Homolog; Regulatory Protein TSC-22; Cerebral Protein 2; TGFB1I4; TSC22; Transforming Growth Factor Beta-Stimulated Protein TSC-22
Function
Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
Biological Process
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process positive regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:InterPro
Biological Process transcription by RNA polymerase II Source:ProtInc1 Publication
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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