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Mouse Anti-TRO Recombinant Antibody (CBYJT-4887) (CBMAB-T4433-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBYJT-4887
Antibody Isotype
IgM
Application
WB, IP, IHC-P

Basic Information

Immunogen
Synthetic peptide: SIVGFSGGP conjugated to KLH, corresponding to amino acids 1319-1327 of Human Trophinin
Specificity
Human, Mouse
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1319-1327

Target

Full Name
Trophinin
Introduction
TRO is a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. TRO participates in cell signalling during embryo implantation, and may also be involved in cancer formation.
Entrez Gene ID
Human7216
Mouse56191
UniProt ID
HumanQ12816
MouseQ7TSJ9
Alternative Names
Trophinin; MAGE-D3 Antigen; MAGED3; Melanoma Antigen, Family D, 3; MAGE Superfamily Protein; Magphinin; KIAA1114; MAGE-D3
Function
Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion.
Biological Process
Biological Process embryo implantation Source:ProtInc1 Publication
Biological Process homophilic cell adhesion via plasma membrane adhesion molecules Source:ProtInc1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
intrinsic component of plasma membrane
nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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