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Rat Anti-Treml4 Recombinant Antibody (CBYJT-4631) (CBMAB-T4161-YJ)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-4631
Antibody Isotype
IgG2a
Application
FC, CyTOF

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse TREML4/TLT-4, Gly25-Pro195, Accession # Q3LRV9
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 25-195

Target

Full Name
Triggering Receptor Expressed On Myeloid Cells Like 4
Introduction
Treml4 positively regulates Toll-like receptor signaling via TLR7, TLR9 and TLR13 in neutrophils and splenic macrophages. It regulates TLR7 signaling by controlling ligand-induced recruitment of TLR7 from the endoplasmic reticulum to endosomes and lysosomes.
Entrez Gene ID
224840
UniProt ID
Q3LRV9
Alternative Names
TLT4; IDCP1; TLT-4; Treml3; BB137214; 5031403H21Rik
Function
Positively regulates Toll-like receptor TLR7 signaling in macrophages.
Biological Process
Biological Process innate immune response Source:UniProtKB-KW
Biological Process positive regulation of toll-like receptor 7 signaling pathway Source:UniProtKB1 Publication
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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