Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-TNFRSF8 Recombinant Antibody (CBYY-C2005) (CBMAB-C3443-YY)


See all TNFRSF8 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2005
Antibody Isotype
IgG2
Application
FC, WB, Activ

Basic Information

Immunogen
Human recombinant TNFRSF8 EC domain
Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Preservative
PBS
Concentration
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNF receptor superfamily member 8
Entrez Gene ID
943
UniProt ID
P28908
Alternative Names
Vascular Cell Adhesion Molecule 1; CD106 Antigen; INCAM-100; Vascular Cell Adhesion Protein 1; V-CAM 1; VCAM-1; CD106;
Function
Receptor for TNFSF8/CD30L (PubMed:8391931).
May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898).
Biological Process
Biological Process cellular response to mechanical stimulus Source:UniProtKB1 Publication
Biological Process negative regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of TRAIL production Source:UniProtKB1 Publication
Biological Process positive regulation of tumor necrosis factor production Source:UniProtKB1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Isoform 1
Cell membrane
Isoform 2
Cytoplasm
Topology
Extracellular: 19-385
Helical: 386-406
Cytoplasmic: 407-595
PTM
Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832).
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TNFRSF8 Recombinant Antibody (CBYY-C2005)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quoteOnline Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry