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Rat Anti-Tnfrsf12a Recombinant Antibody (CBYJT-3711) (CBMAB-T3091-YJ)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-3711
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant mouse TWEAK R/TNFRSF12, Glu28-Trp79, Accession # Q9CR75
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 28-79

Target

Full Name
tumor necrosis factor receptor superfamily, member 12A
Introduction
Tnfrsf12a is a receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types. It promotes angiogenesis and the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.
Entrez Gene ID
27279
UniProt ID
Q9CR75
Alternative Names
Fn14; HPIP; C87282; TweakR; TWEAK-R; AI255180
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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