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Mouse Anti-THAP5 Recombinant Antibody (CBYJT-2908) (CBMAB-T2143-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2908
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
THAP5 (NP_872335.1, aa1-233) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-233

Target

Full Name
THAP5
Introduction
THAP5 (THAP Domain Containing 5) has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952). It may be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).
Entrez Gene ID
168451
UniProt ID
Q7Z6K1
Alternative Names
THAP Domain Containing 5
Function
Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952).
May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).
Biological Process
Biological Process cell cycleSource:UniProtKB-KW
Biological Process negative regulation of cell cycleSource:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase IISource:ARUK-UCL1 Publication
Cellular Location
Nucleus
PTM
Cleaved by HTRA2 during apoptosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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