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Rabbit Anti-TGM6 Recombinant Antibody (BA0083) (CBMAB-0869CQ)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
BA0083
Antibody Isotype
IgG
Application
FC, IHC-P, WB

Basic Information

Immunogen
Human Transglutaminase 6 aa 1-100
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Transglutaminase 6
Introduction
The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Entrez Gene ID
Human343641
Mouse241636
Rat296152
UniProt ID
HumanO95932
MouseQ6YCI4
RatF1M4T7
Alternative Names
TG6; TGY; SCA35; TGM3L; dJ734P14.3
Function
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Biological Process
Peptide cross-linking
Cellular Location
Cytoplasm
Involvement in disease
Spinocerebellar ataxia 35 (SCA35):
A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA35 patients commonly show upper limb involvement and torticollis. There is no cognitive impairment.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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