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Mouse Anti-TCN1 Recombinant Antibody (CBYJT-2319) (CBMAB-T1430-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2319
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
transcobalamin I (vitamin B12 binding protein, R binder family)
Introduction
TCN1 is a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. TCN1 is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
Entrez Gene ID
6947
UniProt ID
P20061
Alternative Names
Transcobalamin 1; Haptocorrin; Transcobalamin I (Vitamin B12 Binding Protein, R Binder Family); Transcobalamin I; Haptocorin; Protein R; TC-1
Function
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Biological Process
Biological Process cobalamin transportIBA:GO_Central1 Publication
Biological Process cobalt ion transportIEA:UniProtKB-KW
Cellular Location
Secreted
PTM
Contains about 30% carbohydrates.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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