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Mouse Anti-TCN1 Recombinant Antibody (3F10) (CBMAB-A8983-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3F10
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
TCN1 (AAH18632, 1 a.a. ~ 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
transcobalamin I (vitamin B12 binding protein, R binder family)
Introduction
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq]
Entrez Gene ID
6947
UniProt ID
P20061
Alternative Names
TC1; TCI
Function
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Biological Process
Biological Process cobalamin transportIBA:GO_Central1 Publication
Biological Process cobalt ion transportIEA:UniProtKB-KW
Cellular Location
Secreted
PTM
Contains about 30% carbohydrates.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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