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Mouse Anti-SYAP1 Recombinant Antibody (CBXS-5536) (CBMAB-S2743-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5536
Antibody Isotype
IgG2a
Application
IP

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Tissue culture supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SYAP1
Introduction
This protein plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation.
Entrez Gene ID
94056
UniProt ID
Q96A49
Alternative Names
FLJ14495; PRO3113
Function
Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation (PubMed:23300339).
Biological Process
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process cellular response to epidermal growth factor stimulusIMP:UniProtKB1 Publication
Biological Process cellular response to insulin stimulusIMP:UniProtKB1 Publication
Biological Process cellular response to insulin-like growth factor stimulusIMP:UniProtKB1 Publication
Biological Process cellular response to platelet-derived growth factor stimulusIMP:UniProtKB1 Publication
Biological Process positive regulation of fat cell differentiationIMP:UniProtKB1 Publication
Biological Process positive regulation of protein serine/threonine kinase activityIMP:UniProtKB1 Publication
Biological Process regulation of short-term neuronal synaptic plasticityIBA:GO_Central1 Publication
Biological Process TORC2 signalingIMP:UniProtKB1 Publication
Cellular Location
Cytoplasm, perinuclear region
Golgi apparatus
Perikaryon
Cell projection, axon
Cell projection, dendrite
Cell projection, growth cone
Presynaptic cell membrane
Postsynaptic cell membrane
Membrane
Localizes to cholinergic neuromuscular junctions and in actin-rich growth cone regions (By similarity).
Membrane-associated in a epidermal growth factor (EGF)-dependent manner (PubMed:23300339).
PTM
Phosphorylated. Phosphorylation increases in a mTORC2-mediated manner in response to epidermal growth factor (EGF) stimulation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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