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Rabbit Anti-STK17B Recombinant Antibody (CBYCD-513) (CBMAB-D2253-YC)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
CBYCD-513
Antibody Isotype
IgG
Application
ICC, IF, IP, WB

Basic Information

Immunogen
A synthetic peptide corresponding to residues 200-300 a.a. in human DRAK2 was used as an immunogen
Specificity
Human, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
serine/threonine kinase 17b (apoptosis-inducing)
Introduction
STK17B has broad expression in bone marrow (RPKM 54.0), lymph node (RPKM 45.0) and 18 other tissues. STK17B phosphorylates myosin light chains and acts as a positive regulator of apoptosis.
Entrez Gene ID
Human9262
Mouse98267
UniProt ID
HumanO94768
MouseQ8BG48
Alternative Names
DRAK2
Function
Phosphorylates myosin light chains (By similarity).
Acts as a positive regulator of apoptosis.
Biological Process
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of apoptotic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of fibroblast apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein autophosphorylationISS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Cell membrane
Endoplasmic reticulum-Golgi intermediate compartment
Colocalizes with STK17B at the plasma membrane.
PTM
Autophosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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