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Mouse Anti-STK17B Recombinant Antibody (2C3) (CBMAB-S2837-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2C3
Antibody Isotype
IgG2b, κ
Application
ELISA, IF, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Concentration
0.37 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
serine/threonine kinase 17b (apoptosis-inducing)
Entrez Gene ID
9262
UniProt ID
O94768
Alternative Names
DRAK2
Function
Phosphorylates myosin light chains (By similarity).
Acts as a positive regulator of apoptosis.
Biological Process
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of apoptotic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of fibroblast apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein autophosphorylationISS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Cell membrane
Endoplasmic reticulum-Golgi intermediate compartment
Colocalizes with STK17B at the plasma membrane.
PTM
Autophosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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