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Mouse Anti-SRR Recombinant Antibody (CBXS-4775) (CBMAB-S2002-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4775
Antibody Isotype
IgG1
Application
FC, IF, IHC, IHC-P, WB

Basic Information

Immunogen
Recombinant full length human SRR(NP_068766) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Serine Racemase
Introduction
SRR (Serine Racemase) is a Protein Coding gene. Diseases associated with SRR include Streptococcal Meningitis and Vitamin E, Familial Isolated Deficiency Of. Among its related pathways are Metabolism and Glycine, serine and threonine metabolism. Gene Ontology (GO) annotations related to this gene include calcium ion binding and magnesium ion binding.
Entrez Gene ID
63826
UniProt ID
Q9GZT4
Alternative Names
Serine Racemase; L-Serine Ammonia-Lyase; D-Serine Ammonia-Lyase; L-Serine Dehydratase; D-Serine Dehydratase; EC 5.1.1.18;
Function
Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Biological Process
Biological Process agingIEA:Ensembl
Biological Process brain developmentIEA:Ensembl
Biological Process D-serine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process D-serine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-serine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process pyruvate biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process response to morphineIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process serine family amino acid metabolic processISS:UniProtKB
Cellular Location
apical part of cell
cytoplasm
cytosol
neuronal cell body
plasma membrane
PTM
S-nitrosylated, leading to decrease the enzyme activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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