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Mouse Anti-SNAPC5 (C-Term) Recombinant Antibody (CBXS-3539) (CBMAB-S6268-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3539
Application
WB

Basic Information

Immunogen
Synthetic peptide corresponding to the C-terminal region of human SNAPC5
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
C-Term

Target

Full Name
small nuclear RNA activating complex, polypeptide 5, 19kDa
Introduction
This gene encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes. This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription. The encoded protein may play a role in stabilizing this complex. A pseudogene of this gene has been identified on chromosome 6.
Entrez Gene ID
10302
UniProt ID
O75971
Alternative Names
Small Nuclear RNA Activating Complex Polypeptide 5; SnRNA-Activating Protein Complex 19 KDa Subunit; SNAPc 19 KDa Subunit; SNAPc Subunit 5; SNAP19; Small Nuclear RNA Activating Complex, Polypeptide 5, 19kDa; Small Nuclear RNA Activating Complex, Polypeptide 5, 19kD; Small Nuclear RNA-Activating Complex Polypeptide 5; SnRNA-Activating Protein Complex Subunit 5;
Function
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Biological Process
Biological Process snRNA transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:GO_Central
Biological Process snRNA transcription by RNA polymerase IIIManual Assertion Based On ExperimentIDA:GO_Central
Biological Process transcription initiation at RNA polymerase III promoterIEA:InterPro
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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