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Rabbit Anti-SLC22A3 Recombinant Antibody (CBXS-1555) (CBMAB-S4404-CQ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-1555
Antibody Isotype
IgG
Application
WB, IHC-P, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 22 Member 3
Introduction
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.
Entrez Gene ID
6581
UniProt ID
O75751
Alternative Names
Solute Carrier Family 22 Member 3; Extraneuronal Monoamine Transporter; Organic Cation Transporter 3; Solute Carrier Family 22 (Extraneuronal Monoamine Transporter), Member 3; Solute Carrier Family 22 (Organic Cation Transporter), Member 3; OCT3; EMTH; EMT; EMT Organic Cation Transporter 3;
Function
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
Biological Process
Biological Process dopamine uptakeManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process epinephrine uptakeManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process histamine metabolic processManual Assertion Based On ExperimentTAS:ARUK-UCL
Biological Process histamine uptakeManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process monoamine transportManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process monocarboxylic acid transportIEA:Ensembl
Biological Process neurotransmitter transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process norepinephrine uptakeManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process organic anion transportISS:ARUK-UCL
Biological Process organic cation transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process purine-containing compound transmembrane transportTAS:Reactome
Biological Process quaternary ammonium group transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process regulation of appetiteIEA:Ensembl
Biological Process serotonin uptakeManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process toxin transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process transport across blood-brain barrier2 PublicationsNAS:ARUK-UCL
Biological Process xenobiotic transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Cellular Location
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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