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Rabbit Anti-SLC18A1 Recombinant Antibody (BA0316) (CBMAB-0842CQ)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
BA0316
Antibody Isotype
IgG
Application
FC, WB

Basic Information

Immunogen
Synthetic peptide from Human VMAT1
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 18 (vesicular monoamine), member 1
Introduction
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane.Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells.
Entrez Gene ID
Human6570
Mouse110877
Rat25693
UniProt ID
HumanP54219
MouseQ8R090
RatQ01818
Alternative Names
CGAT; VAT1; VMAT1
Function
Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells.
Biological Process
Biological Process aminergic neurotransmitter loading into synaptic vesicleManual Assertion Based On ExperimentIBA:GO_Central
Biological Process monoamine transportManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Isoform 1
Cytoplasmic vesicle membrane
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane Annotation
Isoform 2
Endoplasmic reticulum membrane
Topology
Cytoplasmic: 1-21
Helical: 22-42
Lumenal: 43-138
Helical: 139-158
Cytoplasmic: 159-167
Helical: 168-188
Lumenal: 189-197
Helical: 198-218
Cytoplasmic: 219-227
Helical: 228-250
Lumenal: 251-256
Helical: 257-279
Cytoplasmic: 280-299
Helical: 300-319
Lumenal: 320-335
Helical: 336-360
Cytoplasmic: 361-365
Helical: 366-386
Lumenal: 387-391
Helical: 392-412
Cytoplasmic: 413-422
Helical: 423-443
Lumenal: 444-448
Helical: 449-470
Cytoplasmic: 471-525
More Infomation
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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