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Mouse Anti-SLC14A1 Recombinant Antibody (CBXS-1965) (CBMAB-S0149-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1965
Antibody Isotype
IgG2b
Application
FC

Basic Information

Immunogen
NS0 mouse myeloma cell line transfected with human SLC14A1, Accession # Q13336
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
A saline solution, BSA
Preservative
Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 14 Member 1 (Kidd Blood Group)
Introduction
The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system.
Entrez Gene ID
6563
UniProt ID
Q13336
Alternative Names
Solute Carrier Family 14 Member 1 (Kidd Blood Group); Solute Carrier Family 14 (Urea Transporter), Member 1 (Kidd Blood Group); Urea Transporter, Erythrocyte; Kidd Blood Group; HUT11; RACH1; UT1; UTE; JK; Solute Carrier Family 14 (Urea Transporter), Member 1;
Function
Mediates the transport of urea driven by a concentration gradient across the cell membrane of erythrocytes (PubMed:7989337, PubMed:10514515, PubMed:7797558, PubMed:8997401).
Also mediates the transport of urea across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).
Facilitates water transport in erythrocytes (By similarity).
Biological Process
Biological Process establishment of localization in cellIEA:Ensembl
Biological Process transmembrane transportTAS:Reactome
Biological Process urea transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process urea transportManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
Basolateral cell membrane
Restricted to the basolateral membrane in various portions of the urothelium.
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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