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Mouse Anti-SERBP1 Recombinant Antibody (1G5-2D7) (CBMAB-A7987-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1G5-2D7
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
SERBP1 (AAH02488, 1 a.a. ~ 402 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SERPINE1 mRNA binding protein 1
Entrez Gene ID
26135
UniProt ID
Q8NC51
Alternative Names
CGI-55; CHD3IP; DKFZp564M2423; FLJ90489; HABP4L; PAI-RBP1; PAIRBP1
Function
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation (PubMed:28695742).
Biological Process
Biological Process PML body organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of mRNA stability1 PublicationNAS:HGNC-UCL
Cellular Location
Cytoplasm
Nucleus
Cytoplasm, perinuclear region
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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