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Mouse Anti-REEP5 Recombinant Antibody (4D2) (CBMAB-R2026-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4D2
Antibody Isotype
IgG2a
Application
WB, IHC, FC

Basic Information

Immunogen
Full length human recombinant protein of human REEP5 (NP_005660) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
1 mg/mL

Target

Full Name
Receptor Accessory Protein 5
Introduction
REEP5 (Receptor Accessory Protein 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. An important paralog of this gene is REEP6.
Entrez Gene ID
7905
UniProt ID
Q00765
Alternative Names
Receptor Accessory Protein 5; Polyposis Locus Protein 1; Polyposis Coli Region Hypothetical Protein DP1; Deleted In Polyposis 1; C5orf18; DP1; TB2;
Function
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
Biological Process
Biological Process endoplasmic reticulum membrane organizationISS:UniProtKB
Biological Process endoplasmic reticulum organizationISS:FlyBase
Biological Process regulation of intracellular transportISS:FlyBase
Cellular Location
Endoplasmic reticulum membrane
Sarcoplasmic reticulum membrane
Localizes to endoplasmic reticulum tubular network (PubMed:23969831).
In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity).
Topology
Cytoplasmic: 1-34
Helical: 35-51
Lumenal: 52-53
Helical: 54-74
Cytoplasmic: 75-84
Helical: 85-103
Lumenal: 104-105
Helical: 106-123
Cytoplasmic: 124-189
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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