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Mouse Anti-REEP5 Recombinant Antibody (3G11) (CBMAB-A0984-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3G11
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
C5orf18 (NP_005660, 113 a.a. ~ 184 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Receptor Accessory Protein 5
Entrez Gene ID
7905
UniProt ID
Q00765
Alternative Names
C5orf18; D5S346; DP1; MGC70440; TB2
Function
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
Biological Process
Biological Process endoplasmic reticulum membrane organizationISS:UniProtKB
Biological Process endoplasmic reticulum organizationISS:FlyBase
Biological Process regulation of intracellular transportISS:FlyBase
Cellular Location
Endoplasmic reticulum membrane
Sarcoplasmic reticulum membrane
Localizes to endoplasmic reticulum tubular network (PubMed:23969831).
In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity).
Topology
Cytoplasmic: 1-34
Helical: 35-51
Lumenal: 52-53
Helical: 54-74
Cytoplasmic: 75-84
Helical: 85-103
Lumenal: 104-105
Helical: 106-123
Cytoplasmic: 124-189
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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