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Mouse Anti-PPP1R17 Recombinant Antibody (CBWJC-4309) (CBMAB-C5673WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-4309
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human C7ORF16 (NP_006649) produced in E.coli
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS (PH 7.3), 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Protein Phosphatase 1 Regulatory Subunit 17
Introduction
PPP1R17 (Protein Phosphatase 1 Regulatory Subunit 17) is a Protein Coding gene. Diseases associated with PPP1R17 include Hypercholesterolemia, Familial. Among its related pathways are Long-term depression. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity and phosphatase inhibitor activity.
Entrez Gene ID
10842
UniProt ID
O96001
Alternative Names
GSBS; C7orf16
Function
Inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes.
Biological Process
Central nervous system development1 PublicationNAS:UniProtKB
Intracellular signal transduction1 PublicationNAS:UniProtKB
Regulation of phosphatase activityISS:UniProtKB
PTM
Substrate for cGMP-dependent protein kinase. Phosphorylated by PRKG1 isoform alpha. Phosphorylation of Thr-68 and Thr-119 is required for its phosphatase activity (By similarity).
Substrate for cGMP-dependent protein kinase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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