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Mouse Anti-PIH1D1 Recombinant Antibody (G-10) (CBMAB-N4089-WJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
G-10
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PIH1 Domain Containing 1
Introduction
PIH1D1 (PIH1 Domain Containing 1) is a Protein Coding gene.
Entrez Gene ID
Human55011
Mouse68845
Rat292898
UniProt ID
HumanQ9NWS0
MouseQ9CQJ2
RatQ4V7F5
Alternative Names
PIH1 Domain Containing 1; Nucleolar Protein 17 Homolog; NOP17; PIH1 Domain-Containing Protein 1;
Function
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026).
Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451).
Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032).
Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Biological Process
Box C/D snoRNP assemblyManual Assertion Based On ExperimentIMP:BHF-UCL
Chromatin remodelingManual Assertion Based On ExperimentIMP:UniProtKB
Epithelial cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Establishment of protein localization to chromatinManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H3-K9 dimethylationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H3-K9 trimethylationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H4-K16 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of glucose mediated signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of histone H3-K9 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of histone H4 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein serine/threonine kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein-containing complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of TORC1 signalingManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription of nucleolar large rRNA by RNA polymerase IManual Assertion Based On ExperimentIMP:UniProtKB
Protein stabilization2 PublicationsIC:ComplexPortal
Regulation of histone H3-K4 methylationManual Assertion Based On ExperimentIMP:UniProtKB
rRNA processingManual Assertion Based On ExperimentIBA:GO_Central
SnoRNA localizationManual Assertion Based On ExperimentIMP:UniProtKB
TORC1 complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

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