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Mouse Anti-PCYOX1 Recombinant Antibody (5E151) (CBMAB-P1113-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
5E151
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
Human PCYOX1 (aa1-506) with GST Tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-506

Target

Full Name
prenylcysteine oxidase 1
Introduction
Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product.
Entrez Gene ID
51449
UniProt ID
Q9UHG3
Alternative Names
Prenylcysteine Oxidase 1; Prenylcysteine Lyase; EC 1.8.3.5; PCL1; KIAA0908;
Function
Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (PubMed:10585463, PubMed:11078725, PubMed:12186880).
Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity).
Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (PubMed:10585463).
Biological Process
Chloride transmembrane transportIEA:Ensembl
Prenylated protein catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Prenylcysteine catabolic processIEA:Ensembl
Cellular Location
Lysosome
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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