Mouse Anti-OTOP2 (AA 423-493) Recombinant Antibody (CBXO-0274) (CBMAB-O0693-CQ)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBXO-0274

Antibody Isotype

IgG1, Κ

Application

ELISA, WB

Basic Information

Immunogen

OTOP2 (NP_835454, 423aa-493aa) partial Recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG1, Κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 423-493

Target

Full Name

Otopetrin 2

Introduction

OTOP2 (Otopetrin 2) is a Protein Coding gene. An important paralog of this gene is OTOP3.

Entrez Gene ID

92736

UniProt ID

Q7RTS6

Alternative Names

Otopetrin 2; Otopetrin-2

Function

Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.

Biological Process

Proton transmembrane transportISS:UniProtKB

Cellular Location

Cell membrane

More Infomation

References

Bian, Y., Gao, Y., Lu, C., Tian, B., Xin, L., Lin, H., ... & Wang, L. (2023). Genome-wide methylation profiling identified methylated KCNA3 and OTOP2 as promising diagnostic markers for esophageal squamous cell carcinoma. Chinese Medical Journal, 10-1097.

Guo, S., & Sun, Y. (2022). OTOP2, inversely modulated by miR-3148, inhibits CRC cell migration, proliferation and epithelial–mesenchymal transition: evidence from bioinformatics data mining and experimental verification. Cancer Management and Research, 1371-1384.

Qu, H., Su, Y., Yu, L., Zhao, H., & Xin, C. (2019). Wild‐type p53 regulates OTOP 2 transcription through DNA loop alteration of the promoter in colorectal cancer. FEBS open bio, 9(1), 26-34.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Rabbit Anti-OTOP2 Recombinant Antibody (CBXO-0160)

Rabbit Anti-OTOP2 Recombinant Antibody (BA0373)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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