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Mouse Anti-NUCB1 Recombinant Antibody (1A5) (CBMAB-1634-CN)


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Summary

Host Animal
Mouse
Specificity
Human, Monkey
Clone
1A5
Antibody Isotype
IgG1
Application
WB, FC, IF, IHC, IHC-P

Basic Information

Immunogen
Full length human recombinant protein of human NUCB1 (NP_006175) produced in HEk293T cell.
Specificity
Human, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nucleobindin 1
Introduction
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. Major calcium-binding protein of the Golgi. The protein may have a role in calcium homeostasis (By similarity).
Entrez Gene ID
Human4924
Monkey718380
UniProt ID
HumanQ02818
MonkeyF6ZVE3
Alternative Names
NUC; CALNUC
Function
Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity).
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).
Biological Process
Small GTPase mediated signal transductionISS:UniProtKB
Cellular Location
Golgi apparatus, cis-Golgi network membrane
Cytoplasm
Secreted
A small fraction of the protein may be cytoplasmic.
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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