Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-NPS Recombinant Antibody (CBWJN-1521) (CBMAB-N3261-WJ)


See all NPS antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBWJN-1521
Application
WB, ICC, IHC-P, IHC-F, ELISA

Basic Information

Specificity
Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Neuropeptide S
Introduction
Modulates arousal and anxiety. May play an important anorexigenic role (By similarity). Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (PubMed:15312648, PubMed:16790440).
Entrez Gene ID
100360071
UniProt ID
P0C0P7
Alternative Names
Neuropeptide S; Prepro-Neuropeptide S;
Function
Modulates arousal and anxiety. May play an important anorexigenic role (By similarity).
Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (PubMed:15312648, PubMed:16790440).
Biological Process
Neuropeptide signaling pathwayIEA:UniProtKB-KW
Positive regulation of action potentialManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of circadian sleep/wake cycle, wakefulnessIEA:Ensembl
Positive regulation of synaptic transmission, GABAergicManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of synaptic transmission, glutamatergicManual Assertion Based On ExperimentIBA:GO_Central
Visual learningIEA:Ensembl
Cellular Location
Secreted
More Infomation

Shirsath, K. R., Patil, V. K., Awathale, S. N., Goyal, S. N., & Nakhate, K. T. (2024). Pathophysiological and Therapeutic Implications of Neuropeptide S System in Neurological Disorders. Peptides, 171167.

Song, C., Zhu, Z. C., Liu, C. C., Yun, W. X., Wang, Z. Y., Lu, G. Y., ... & Li, F. (2024). Neuropeptide S Receptor 1 variant (I107N) regulates behavioral characteristics and NPS effect in mice in a sex-dependent manner. Neuropharmacology, 242, 109771.

Akçalı, İ., Akkan, S. S., & Bülbül, M. (2023). The regulatory role of central neuropeptide-S in locomotion. Peptides, 170, 171110.

Markiewicz-Gospodarek, A., Markiewicz, R., Dobrowolska, B., Rahnama, M., & Łoza, B. (2022). Relationship of neuropeptide S (NPS) with neurocognitive, clinical, and electrophysiological parameters of patients during structured rehabilitation therapy for schizophrenia. Journal of Clinical Medicine, 11(18), 5266.

Huang, D., Zhang, R., Gasparini, S., McDonough, M. C., Paradee, W. J., & Geerling, J. C. (2022). Neuropeptide S (NPS) neurons: Parabrachial identity and novel distributions. Journal of Comparative Neurology, 530(18), 3157-3178.

Markiewicz-Gospodarek, A., Kuszta, P., Baj, J., Dobrowolska, B., & Markiewicz, R. (2022). Can Neuropeptide S be an indicator for assessing anxiety in psychiatric disorders?. Frontiers in Public Health, 10, 872430.

Cannella, N., Borruto, A. M., Petrella, M., Micioni Di Bonaventura, M. V., Soverchia, L., Cifani, C., ... & Ubaldi, M. (2022). A Role for Neuropeptide S in Alcohol and Cocaine Seeking. Pharmaceuticals, 15(7), 800.

Botticelli, L., Micioni Di Bonaventura, E., Ubaldi, M., Ciccocioppo, R., Cifani, C., & Micioni Di Bonaventura, M. V. (2021). The Neural Network of Neuropeptide S (NPS): Implications in food intake and gastrointestinal functions. Pharmaceuticals, 14(4), 293.

Kushikata, T., Hirota, K., Saito, J., & Takekawa, D. (2021). Roles of neuropeptide S in anesthesia, analgesia, and sleep. Pharmaceuticals, 14(5), 483.

Grund, T., & Neumann, I. D. (2019). Brain neuropeptide S: via GPCR activation to a powerful neuromodulator of socio-emotional behaviors. Cell and tissue research, 375, 123-132.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-NPS Recombinant Antibody (CBWJN-1521)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry