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Mouse Anti-NCAM1 Monoclonal Antibody (ERIC-1) (CBMAB-1408-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Rat, Cattle
Clone
ERIC-1
Antibody Isotype
IgG1
Application
ELISA, FC, ICC, IF, IHC-Fr, IHC-P, IP, WB

Basic Information

Immunogen
CD56 positive cells
Specificity
Human, Rat, Cattle
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Neural Cell Adhesion Molecule 1
Introduction
NCAM is a cell adhesion protein which is a member of the immunoglobulin superfamily. NCAM is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. NCAM also has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells.
Entrez Gene ID
Human4684
Cattle281941
Rat24586
UniProt ID
HumanP13591
CattleP31836
RatP13596
Alternative Names
Neural Cell Adhesion Molecule 1; NCAM; Antigen Recognized By Monoclonal Antibody 5.1H11; Neural Cell Adhesion Molecule, NCAM; CD56 Antigen; N-CAM-1; NCAM-1; MSK39; CD56;
Function
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

(Microbial infection) Acts as a receptor for rabies virus.

(Microbial infection) Acts as a receptor for Zika virus.
Biological Process
Cell adhesion Source: ProtInc
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL
Cellular Location
Isoform 1&2&3&4: Cell membrane
Isoform 5&6: Secreted
Topology
Extracellular: 20-718
Helical: 719-739
Cytoplasmic: 740-858
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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