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Mouse Anti-MLF2 Recombinant Antibody (CBFYM-2284) (CBMAB-M2469-FY)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2284

Antibody Isotype

IgG1

Application

FC, WB

Basic Information

Immunogen

Full length human recombinant protein of human MLF2(NP_005430) produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

2.48 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Myeloid Leukemia Factor 2

Introduction

MLF2 is a Protein Coding gene. Diseases associated with MLF2 include Myeloid Leukemia and Leukemia. An important paralog of this gene is MLF1.

Entrez Gene ID

UniProt ID

Alternative Names

Myeloid Leukemia Factor 2; Myelodysplasia-Myeloid Leukemia Factor 2; NTN4

Biological Process

Regulation of transcription, DNA-templated Source: GO_Central

Cellular Location

Nucleus
Cytoplasm

More Infomation

References

Fang, D., Hu, H., Zhao, K., Xu, A., Yu, C., Zhu, Y., ... & Mei, Y. (2023). MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis. Advanced Science, 10(26), 2303336.

Ogunleye, A. J., Romanova, E., & Medvedeva, Y. A. (2021). Genome-wide regulation of CpG methylation by ecCEBPα in acute myeloid leukemia. F1000Research, 10.

Yang, J., Cao, D., Zhang, Y., Ou, R., Yin, Z., Liu, Y., ... & Fei, J. (2020). The role of phosphorylation of MLF2 at serine 24 in BCR-ABL leukemogenesis. Cancer Gene Therapy, 27(1-2), 98-107.

Huang, D., Liu, C., Sun, X., Sun, X., Qu, Y., Tang, Y., ... & Tong, T. (2020). CRL4DCAF8 and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs). Biochemical and Biophysical Research Communications, 529(2), 127-132.

Rampello, A. J., Laudermilch, E., Vishnoi, N., Prophet, S. M., Shao, L., Zhao, C., ... & Schlieker, C. (2020). Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2. Journal of Cell Biology, 219(6).

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Antibody Pairs

MLF2 Matched Antibody Pair (738)

MLF2 Matched Antibody Pair (739)

Related Products

MLF2 Matched Antibody Pair (739)

Mouse Anti-MLF2 Recombinant Antibody (2F6-1E3)

MLF2 Matched Antibody Pair (738)

Mouse Anti-MLF2 (AA 1-248) Recombinant Antibody (CBFYM-2285)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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