Rabbit Anti-MELTF Recombinant Antibody (CBFYM-2060) (CBMAB-M2241-FY)

Name: Rabbit Anti-MELTF Recombinant Antibody (CBFYM-2060)
SKU: CBMAB-M2241-FY
Rating: 5 (1 reviews)

See all MELTF antibodies

Online Inquiry

Datasheet

Summary

Host Animal

Rabbit

Specificity

Human, Mouse, Rat

Clone

CBFYM-2060

Antibody Isotype

IgG

Application

ELISA, WB

Basic Information

Immunogen

Human MFI2

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Melanotransferrin

Introduction

The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.

Entrez Gene ID

Human	4241
Mouse	30060
Rat	288038

UniProt ID

Human	P08582
Mouse	Q9R0R1
Rat	D4ADK7

Alternative Names

Melanotransferrin; Antigen P97 (Melanoma Associated) Identified By Monoclonal Antibodies 133.2 And 96.5; Membrane-Bound Transferrin-Like Protein; Melanoma-Associated Antigen P97; MAP97; MFI2

Function

Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.

Biological Process

Iron ion homeostasis Source: UniProtKB-KW
Iron ion transport Source: UniProtKB
Negative regulation of substrate adhesion-dependent cell spreading Source: UniProtKB
Positive regulation of extracellular matrix disassembly Source: UniProtKB
Positive regulation of plasminogen activation Source: UniProtKB

Cellular Location

Cell membrane

More Infomation

References

Mao, Y., Wang, M., Xiong, Y., Wen, X., Zhang, M., Ma, L., & Zhang, Y. (2023). MELTF might regulate ferroptosis, pyroptosis, and autophagy in platelet-rich plasma-mediated endometrial epithelium regeneration. Reproductive Sciences, 30(5), 1506-1520.

Zhang, L., & Shi, L. (2023). The E2F1/MELTF axis fosters the progression of lung adenocarcinoma by regulating the Notch signaling pathway. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 827, 111837.

Lu, X., Wang, J., Wang, W., Lu, C., Qu, T., He, X., ... & Zhang, E. (2022). Copy number amplification and SP1-activated lncRNA MELTF-AS1 regulates tumorigenesis by driving phase separation of YBX1 to activate ANXA8 in non-small cell lung cancer. Oncogene, 41(23), 3222-3238.

Chai, J., Qin, L., Zhang, G., Hua, P., & Jin, C. (2022). Long non-coding MELTF antisense RNA 1 promotes and prognosis the progression of non-small cell lung cancer by targeting miR-1299. Bioengineered, 13(4), 10594-10604.

Ding, L., Liu, T., Qu, Y., Kang, Z., Guo, L., Zhang, H., ... & Zhang, S. (2021). lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression. Molecular Therapy-Nucleic Acids, 26, 787-797.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Rabbit Anti-MELTF Recombinant Antibody (CBFYM-2060)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Human Anti-MELTF Recombinant Antibody (CBXC-0921)

Rabbit Anti-MELTF (AA 627-655) Recombinant Antibody (CBFYM-0455)

Mouse Anti-MELTF (AA 1-302) Recombinant Antibody (CBFYM-2058)

Mouse Anti-MELTF Recombinant Antibody (SHM72)

Mouse Anti-MELTF Recombinant Antibody (CBFYC-2947)

Mouse Anti-MELTF (AA 1-711) Recombinant Antibody (CBFYM-0218)

Rabbit Anti-MELTF (N-terminus) Recombinant Antibody (CBFYM-2059)

Mouse Anti-MELTF (AA 21-302) Recombinant Antibody (CBFYM-2056)

Rabbit Anti-MELTF (C-terminus) Recombinant Antibody (CBFYM-2054)

Mouse Anti-MELTF Recombinant Antibody (214D4)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: