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Mouse Anti-MED6 Recombinant Antibody (CBFYM-2013) (CBMAB-M2191-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2013
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Immunogen
Human MED10 (25kD)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Mediator Complex Subunit 6
Introduction
MED6 is a Protein Coding gene. Among its related pathways are Gene Expression and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha. Gene Ontology annotations related to this gene include transcription factor binding and RNA polymerase II transcription cofactor activity.
Entrez Gene ID
10001
UniProt ID
O75586
Alternative Names
Mediator Complex Subunit 6; Activator-Recruited Cofactor 33 KDa Component; Renal Carcinoma Antigen NY-REN-28; ARC33; Mediator Of RNA Polymerase II Transcription, Subunit 6 Homolog (S. Cerevisiae); Mediator Of RNA Polymerase II Transcription Subunit 6; CTD-2540L5.5; NY-REN-28; HMed6
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription by RNA polymerase II Source: MGI
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Stem cell population maintenance Source: Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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