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Mouse Anti-LIPG Recombinant Antibody (CBFYE-1483) (CBMAB-E2116-FY)


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Summary

Host Animal
Mouse
Specificity
Dog, Goat, Human, Pig, Rabbit
Clone
CBFYE-1483
Antibody Isotype
IgG2a
Application
IHC-Fr, IF

Basic Information

Immunogen
This item reacts with an antigen associated with venous endothelial cells. This antibody preferentially stains endothelial cells in medium and small veins, venules and capillaries in all organs. Negative, or weak staining is observed in large veins, arterioles and arteries. Lymphatic endothelium is also negative
Specificity
Dog, Goat, Human, Pig, Rabbit
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
LIPG
Introduction
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family.
Entrez Gene ID
Human9388
Goat102191574
Pig100155736
Rabbit100342293
Dog609249
UniProt ID
HumanQ9Y5X9
GoatA0A452EU23
PigI3LUA0
RabbitG1TKR5
DogE2R774
Alternative Names
EL; EDL; PRO719
Function
Exerts both phospholipase and triglyceride lipase activities (PubMed:12032167, PubMed:10318835, PubMed:10192396).
More active as a phospholipase than a triglyceride lipase (PubMed:12032167).
Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates (PubMed:12032167).
Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins (PubMed:12032167, PubMed:10192396).
Biological Process
Cell population proliferationIEA:Ensembl
Cholesterol homeostasisManual Assertion Based On ExperimentIMP:BHF-UCL
Fatty acid biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
High-density lipoprotein particle remodelingManual Assertion Based On ExperimentIMP:BHF-UCL
Lipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Lipid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Phospholipid catabolic process1 PublicationNAS:BHF-UCL
Phospholipid homeostasisManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of cholesterol transportManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of high-density lipoprotein particle clearanceManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of lipoprotein metabolic processIEA:Ensembl
Response to nutrientIEA:Ensembl
Reverse cholesterol transportManual Assertion Based On ExperimentIMP:BHF-UCL
Triglyceride catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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