Mouse Anti-L3MBTL4 Antibody (4D1) (CBMAB-0607-YC)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

4D1

Antibody Isotype

IgG2b

Application

IP, MA

Basic Information

Immunogen

Recombinant protein

Specificity

Human

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

L3MBTL4

Introduction

L3MBTL4 (L(3)mbt-like 4) is a protein that has transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is L3MBTL3.

Entrez Gene ID

91133

UniProt ID

Q8NA19

Alternative Names

HsT1031

Function

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).

Biological Process

Chromatin organizationIEA:UniProtKB-KW
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

More Infomation

References

Ma, L., Liu, Y., Xu, F., Shen, R., Wang, M., Zhang, Y., ... & Zheng, G. (2023). IL-27-induced, MSC-derived Exosomes Promote MMP3 Expression Through the miR-206/L3MBTL4 Axis in Synovial Fibroblasts. Alternative Therapies in Health and Medicine, AT8854-AT8854.

Hu, C., Zuo, K., Li, K., Gao, Y., Chen, M., Hu, R., ... & Li, J. (2020). p38/JNK is required for the proliferation and phenotype changes of vascular smooth muscle cells induced by L3MBTL4 in essential hypertension. International Journal of Hypertension, 2020.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Antibody Pairs

L3MBTL4 Matched Antibody Pair (677)

Related Products

Mouse Anti-L3MBTL4 Recombinant Antibody (R160.1.1C8)

L3MBTL4 Matched Antibody Pair (677)

Mouse Anti-L3MBTL4 Recombinant Antibody (CBYJL-1041)

Mouse Anti-L3MBTL4 Recombinant Antibody (1B9-1C12)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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