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Armenian Hamster Anti-JAG2 Recombinant Antibody (HMJ2-1) (CBMAB-1045-LY)


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Summary

Host Animal
Armenian Hamster
Specificity
Mouse
Clone
HMJ2-1
Antibody Isotype
IgG
Application
Neutralization

Basic Information

Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
JAG2
Introduction
Putative Notch ligand involved in the mediation of Notch signaling. Plays an essential role during limb, craniofacial and thymic development. May be involved in myogenesis and in the development of peripheral and central nervous systems.
Entrez Gene ID
16450
UniProt ID
Q9QYE5
Alternative Names
sm; Serh; D12Ggc2e; mJagged2-1
Function
Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity).
Biological Process
Auditory receptor cell fate commitmentBy SimilarityISS:UniProtKB
Cell differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Epithelial cell apoptotic process involved in palatal shelf morphogenesisIEA:Ensembl
Gamma-delta T cell differentiationIEA:Ensembl
In utero embryonic developmentIEA:Ensembl
Morphogenesis of embryonic epitheliumIEA:Ensembl
Notch signaling pathway1 PublicationNAS:UniProtKB
Odontogenesis of dentin-containing toothIEA:Ensembl
Positive regulation of Notch signaling pathwayISS:UniProtKB
Regulation of cell adhesionIEA:Ensembl
Regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Respiratory system processIEA:Ensembl
Skeletal system developmentIEA:Ensembl
SpermatogenesisManual Assertion Based On ExperimentIEP:UniProtKB
T cell differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Thymic T cell selectionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 27-1080
Helical: 1081-1101
Cytoplasmic: 1102-1238
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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