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Mouse Anti-HSV-1 gD Recombinant Antibody (CBMW-H0078) (CBMAB-V208-0088-FY)


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Summary

Host Animal
Mouse
Specificity
HSV
Clone
CBMW-H0078
Antibody Isotype
IgG2a
Application
ELISA, IF

Basic Information

Immunogen
HSV 1, specific for gD
Specificity
HSV
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.1% Sodium azide
Purity
>90% by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Herpes simplex virus 1 Glycoprotein D
Introduction
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious.
Entrez Gene ID
2703444
UniProt ID
Q69091
Alternative Names
gD; Envelope glycoprotein D; HSV-1 gD; Human alphaherpesvirus 1
Function
Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM, NECTIN1 and 3-O-sulfated heparan sulfate (By similarity).

May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL.
Biological Process
Entry receptor-mediated virion attachment to host cell Source: UniProtKB-KW
Viral entry into host cell Source: UniProtKB-KW
Cellular Location
Virion membrane; Host Golgi apparatus. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Topology
Virion surface: 26-340
Helical: 341-361
Intravirion: 362-394
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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