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Mouse Anti-HIV-1 p17 Recombinant Antibody (CBMW-H0082) (CBMAB-V208-0093-FY)


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Summary

Host Animal
Mouse
Specificity
HIV
Clone
CBMW-H0082
Antibody Isotype
IgG1
Application
ELISA, IF

Basic Information

Specificity
HIV
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Purity
>95% by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Human Immunodeficiency Virus Type 1 Matrix Protein P17
Introduction
The HIV-1 matrix protein p17 is a structural protein critically involved in most stages of the life cycle of the retrovirus. It participates in the early stages of virus replication as well as in RNA targeting to the plasma membrane, incorporation of the envelope into virions and particle assembly. Besides its well established functions, p17 acts as a viral cytokine that works on preactivated--but not on resting--human T cells promoting proliferation, proinflammatory cytokines release and HIV-1 replication after binding to a cellular receptor (p17R). Thus, p17 might play a key role in the complex network of host-and virus-derived stimulatory factors contributing to create a favourable environment for HIV-1 infection and replication.
Entrez Gene ID
155030
UniProt ID
P04591
Alternative Names
HIV-1 p17; Human immunodeficiency virus-1 p17; human immunodeficiency virus; HIV
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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