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Mouse Anti-GPT Recombinant Antibody (CBYC-A970) (CBMAB-A4443-YC)

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Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBYC-A970
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
Recombinant ALT (Met1-Ser496) expressed in E. coli.
Specificity
Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Glutamic--Pyruvic Transaminase
Introduction
GPT is cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key rol
Entrez Gene ID
UniProt ID
Alternative Names
AAT1; GPT1; ALT1
Function
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).
Biological Process
Biosynthetic process Source: InterPro
Cellular response to insulin stimulus Source: Ensembl
L-alanine catabolic process Source: UniProtKB-UniPathway
Positive regulation of gluconeogenesis Source: Ensembl
Response to starvation Source: Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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