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Mouse Anti-GLYAT Recombinant Antibody (CBLG1-2831) (CBMAB-G3974-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-2831
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human GLYAT(NP_005829) produced in E.coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% NaN3
Concentration
1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
glycine-N-acyltransferase
Introduction
The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
10249
UniProt ID
Q6IB77
Alternative Names
Glycine-N-Acyltransferase; Aralkyl Acyl-CoA:Amino Acid N-Acyltransferase; Benzoyl-Coenzyme A:Glycine N-Acyltransferase; Acyl-CoA:Glycine N-Acyltransferase; Aralkyl Acyl-CoA N-Acyltransferase; Glycine N-Benzoyltransferase; EC 2.3.1.13; HRP-1(CLP);
Function
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Biological Process
Acyl-CoA metabolic process Source: ProtInc
Benzoyl-CoA metabolic process Source: UniProtKB
Glycine metabolic process Source: UniProtKB
Monocarboxylic acid metabolic process Source: UniProtKB
Response to toxic substance Source: ProtInc
Xenobiotic metabolic process Source: Reactome
Cellular Location
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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