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Mouse Anti-GDF7 Recombinant Antibody (1H1) (CBMAB-A3369-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1H1
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
GDF7 (NP_878248, 361 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Growth Differentiation Factor 7
Introduction
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq]
Entrez Gene ID
151449
UniProt ID
Q7Z4P5
Alternative Names
BMP12
Function
May play an active role in the motor area of the primate neocortex.
Biological Process
Activin receptor signaling pathway Source: BHF-UCL
Axon guidance Source: Ensembl
BMP signaling pathway Source: BHF-UCL
Branching morphogenesis of an epithelial tube Source: Ensembl
Cell fate commitment Source: Ensembl
Epithelial cell differentiation Source: Ensembl
Forebrain morphogenesis Source: Ensembl
Gland morphogenesis Source: Ensembl
Midbrain development Source: Ensembl
Morphogenesis of an epithelial fold Source: Ensembl
Pathway-restricted SMAD protein phosphorylation Source: BHF-UCL
Positive regulation of gene expression Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Positive regulation of pathway-restricted SMAD protein phosphorylation Source: BHF-UCL
Positive regulation of tendon cell differentiation Source: Ensembl
Positive regulation of transcription, DNA-templated Source: BHF-UCL
Reproductive structure development Source: Ensembl
Roof plate formation Source: Ensembl
SMAD protein signal transduction Source: GO_Central
Spinal cord association neuron differentiation Source: Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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