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Mouse Anti-GARS1 Recombinant Antibody (6C5) (CBMAB-G2105-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
6C5
Antibody Isotype
IgG2b
Application
IHC-P

Basic Information

Immunogen
Full length human recombinant protein of human GARS (NP_002038) produced in HEK293T cell.ImmunogenType: Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GARS1
Introduction
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Entrez Gene ID
2617
UniProt ID
P41250
Alternative Names
Glycyl-TRNA Synthetase; Diadenosine Tetraphosphate Synthetase; Charcot-Marie-Tooth Neuropathy 2D; AP-4-A Synthetase; EC 6.1.1.14; GlyRS; Charcot-Marie-Tooth Neuropathy; Neuronal Type; D; Glycine--TRNA Ligase;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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