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Rabbit Anti-GABBR2 (phospho S893) Recombinant Antibody (BA0039) (CBMAB-0324CQ)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
BA0039
Antibody Isotype
IgG
Application
IF, IHC-P, WB

Basic Information

Immunogen
Synthetic phosphopeptide from residues surrounding serine 893 of human GABA B Receptor 2
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Introduction
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. Martin et al. (2001) determined that the human GPR51 gene, which they called GABA(B)R2, spans more than 350 kb and contains 2.8-kb of coding region in 19 exons. By radiation hybrid analysis, Ng et al. (1999) localized the GPR51 gene to chromosome 9, proximal to HSN1 (162400). Using a genomic GPR51 clone for fluorescence in situ hybridization, Martin et al. (1999) located GPR51 on chromosome 9q22.1. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. Gamma-aminobutyric acid (GABA) type B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase.
Entrez Gene ID
Human9568
Mouse242425
Rat83633
UniProt ID
HumanO75899
MouseQ80T41
RatO88871
Alternative Names
Gamma-Aminobutyric Acid Type B Receptor Subunit 2; Gamma-Aminobutyric Acid (GABA) B Receptor, 2; G Protein-Coupled Receptor 51; G-Protein Coupled Receptor 51; GABA-B Receptor 2; GABA-B-R2; GABA-BR2; GABABR2; GPRC3B; GPR51; HG20; Gb2; Gamma-Aminobutyric Acid B Receptor 2; GABA-B Receptor, R2 Subunit; HRIHFB2099
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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