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Mouse Anti-FXR2 Recombinant Antibody (CBXF-1981) (CBMAB-F1586-CQ)


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Summary

Host Animal
Mouse
Specificity
Rat, Human
Clone
CBXF-1981
Antibody Isotype
IgG2b
Application
WB, IF

Basic Information

Immunogen
Human FXR2 aa. 520-639
Specificity
Rat, Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FMR1 autosomal homolog 2
Introduction
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.
Entrez Gene ID
Human9513
Rat287433
UniProt ID
HumanP51116
RatB1H2A6
Alternative Names
FMR1 Autosomal Homolog 2; Fragile X Mental Retardation, Autosomal Homolog 2; FMR1L2; Fragile X Mental Retardation Syndrome-Related Protein 2; Fragile X-Mental Retardation 1-Like 2; FXR2P;
Function
RNA-binding protein.
Biological Process
Negative regulation of translation Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Positive regulation of response to DNA damage stimulus Source: GO_Central
Positive regulation of translation Source: GO_Central
Regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
Regulation of filopodium assembly Source: GO_Central
Regulation of mRNA stability Source: GO_Central
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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