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Mouse Anti-FSD1 Recombinant Antibody (CBXF-3712) (CBMAB-F1912-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-3712
Antibody Isotype
IgG2a, κ
Application
ELISA, IP, WB

Basic Information

Immunogen
FSD1 (1 a.a.-309 a.a) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
fibronectin type III and SPRY domain containing 1
Introduction
This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis.
Entrez Gene ID
79187
UniProt ID
Q9BTV5
Alternative Names
Fibronectin Type III And SPRY Domain Containing 1; Fibronectin Type 3 And SPRY Domain Containing 1; Microtubule-Associated Protein GLFND; MID1-Related Protein 1; GLFND; MIR1; Fibronectin Type 3 And SPRY (Spla, Ryanodine) Domain Containing (With Coiled-Coil Motif) 1; Fibronectin Type III And SPRY Domain-Containing Protein 1; Midline 1-Related Protein 1;
Function
May be involved in microtubule organization and stabilization.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Cytoplasmic microtubule organization Source: UniProtKB
Regulation of cell division Source: UniProtKB
Regulation of cytokinesis Source: UniProtKB
Regulation of mitotic spindle organization Source: UniProtKB
Cellular Location
Centrosome; Cytoplasm; Nucleus; Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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